CSK antibody-多抗-深圳欣博盛生物科技有限公司

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CSK antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX74502

规格：50μg

目录价：￥5600

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

CSK antibody

别名:

C-terminal Src kinase

反应种属:

Human, Mouse, Rat

宿主来源:

Goat

实验应用:

ELISA, IHC-P, WB

靶标/特异性:

This antibody recognizes an epitope within the C-terminal region of CSK (c-src tyrosine kinase).

同种型:

IgG

免疫原:

Peptide sequence EQLEHIKTHELHL corresponding to the C-terminal region of CSK (NP_004374.1).

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by affinity chromatography

偶联:

Unconjugated

产品浓度:

0.5 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

TBS, 0.5% BSA, 0.02% Sodium azide.

生产商:

GeneTex

功能与背景:

The protein encoded by this gene is involved in multiple pathways, including the regulation of Src family kinases. It plays an important role in T-cell activation through its association with the protein encoded by the protein tyrosine phosphatase, non-receptor type 22 (PTPN22) gene. This protein also phosphorylates C-terminal tyrosine residues on multiple substrates, including the protein encoded by the SRC proto-oncogene, non-receptor tyrosine kinase gene. Phosphorylation suppresses the kinase activity of the Src family tyrosine kinases. An intronic polymorphism (rs34933034) in this gene has been found to affect B-cell activation and is associated with systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]

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