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折扣/货期| 货号：GTX100027-S | 规格：25μl | 目录价：￥1700 |
| 货号：GTX100027 | 规格：100μl | 目录价：￥4000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
CXCR7 antibody [C1C2], Internal
别名:
atypical chemokine receptor 3 , CMKOR1 , CXC-R7 , CXCR-7 , CXCR7 , GPR159 , RDC-1 , RDC1
产品描述:
CXCR7 antibody recognizes C-X-C chemokine receptor type 7 (CXCR7), now known as atypical chemokine receptor 3 (ACKR3). This chemokine receptor (with a predicted molecular weight of 41 kDa) binds the chemokines CXCL11 and CXCL12 and other non-chemokine ligands such as adrenomedullin and MIF. ACKR3 plays important roles in cardiovascular and neuronal development and acts as a scavenger receptor to regulate both chemokine- and opioid peptide-dependent signaling.
反应种属:
Human, Mouse, Rat
宿主来源:
Rabbit
实验应用:
ELISA, FCM, ICC/IF, IHC-Fr, IHC-P, IP, WB
靶标/特异性:
KO/KD validation is based on published data (PMID: 32366833).
同种型:
IgG
免疫原:
Synthetic peptide encompassing a sequence within the Intracellular domain of human CXCR7. The exact sequence is proprietary.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography.
偶联:
Unconjugated
产品浓度:
0.14 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, 1% BSA, 20% Glycerol, 0.025% ProClin 300.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq]
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