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折扣/货期| 货号：SIH-201-25MG | 规格：25 mg | 目录价：￥1800 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Cyclosporine
别名:
(3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-Ethyl-33-[(1R,2R,4E)-1-hydroxy-2-methyl-4-hexen-1-yl]-6,9,18,24-tetraisobutyl-3,21-diisopropyl-1,4,7,10,12,15,19,25,28-nonamethyl-1,4,7,10,13,16,19,22,25,28,3 1-undecaazacyclotritriacontane-2,5,8,11,14,17,20,23,26,29,32-undecone, Cyclosporin A
产品描述:
Immunosuppressant
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
1202.63
产品形式:
White Solid
产地:
加拿大
功能与背景:
Cyclosporin A is a hydrophobic cyclic peptide, and is a potent immune-suppressant and antifungal. It acts via its ability to bind to a family of intracellular proteins (1). The immunosuppressant action is mediated by the complex Cyclosporin-A-cyclophilin that specifically inhibits the Ca2+/calmodulin-dependent serine-threonine-protein phosphatase-2B. This is turn inhibits calcineurin and promotes dephosphorylation of transcription factor NF-AT and T-cell activation (2).
纯度:
>99%
来源:
Synthetic
CAS号:
59865-13-3
分子式:
C62H111N11O12
溶解度:
Soluble to 100 mM in DMSO, 50 mM in ethanol
PubChem CID:
5284373
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