| 货号:V5214SAF-100UG | 规格:100 ug | 目录价:¥6652.1 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Cystic Fibrosis Transmembrane Regulator Antibody / CFTR
产品描述:
Recognizes a protein of 165-170kDa, identified as cystic fibrosis transmembrane conductance regulator (CFTR). CFTR is composed of two membrane-spanning domains (MSD), two nucleotide-binding domains (NBD), and an R domain. It is structurally similar to multidrug resistance (Mdr1) protein and both are members of the superfamily of ATP-binding cassette (ABC) transporters, also known as traffic ATPases, which are implicated in the movement of various substrates. The CFTR protein is a small conductance adenosine 3',5'-cyclic monophosphate (cAMP)-activated chloride ion channel found in the apical membranes of epithelia within the pancreas, airway, intestine, bile duct, sweat gland, and male genital ducts. CFTR is a valuable marker of human pancreatic duct cell development and differentiation.
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P
同种型:
Mouse IgG1, kappa
免疫原:
A recombinant partial protein sequence (within amino acids 550-850) from the human protein was used as the immunogen for the Cystic Fibrosis Transmembrane Regulator antibody.
克隆性:
Recombinant Mouse Monoclonal
克隆号:
rCFTR/8048
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the Cystic Fibrosis Transmembrane Regulator antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
1 mg/ml in 1X PBS; BSA free, sodium azide free
产地:
美国
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