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折扣/货期| 货号：35251-1 g | 规格：1 g | 目录价：￥8362 |
| 货号：35251-100 mg | 规格：100 mg | 目录价：￥1769 |
| 货号：35251-50 mg | 规格：50 mg | 目录价：￥938 |
| 货号：35251-500 mg | 规格：500 mg | 目录价：￥4650 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Dabrafenib (mesylate)
别名:
GSK2118436B
产品描述:
An ATP-competitive Raf kinase inhibitor (IC50s = 0.64, 0.68, and 5 nM for wild-type B-RAF kinase, mutant B-RAFV600E, and wild-type C-RAF kinase, respectively); also inhibits ALK5, LIMK1, SIK2, PDK2, NEK11, CK1, and BRK (IC50s = 11, 15, 27, 57, 20, 41, and 79 nM, respectively) in a panel of 270 kinases at 300 nM; inhibits the growth of 16 cancer cell lines expressing mutant B-RAFV600E (GI50s = 50s = 50s = V600E-expressing A375P melanoma cells; reduces tumor growth in an A375P mouse xenograft model at 3-100 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
519.564609
产品形式:
A solid
纯度:
≥98%
CAS号:
1195768-06-9
分子式:
C23H20F3N5O2S2 • CH3SO3H
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