官网链接
折扣/货期| 货号：35257-1 mg | 规格：1 mg | 目录价：￥1313 |
| 货号：35257-10 mg | 规格：10 mg | 目录价：￥7209 |
| 货号：35257-25 mg | 规格：25 mg | 目录价：￥14713 |
| 货号：35257-5 mg | 规格：5 mg | 目录价：￥5239 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
PF-07321332
别名:
Nirmatrelvir
产品描述:
An inhibitor of SARS-CoV-2 Mpro (Ki = 3.11 nM); inhibits Mpro from SARS-CoV-1, HKU1-CoV, OC43-CoV, and MERS-CoV (Kis = 4.94, 189, 36.4, and 187 nM, respectively), as well as Mpro from NL-63-CoV and 229E CoV (Kis = 226 and 44.4 nM, respectively); selective for these enzymes over several other proteases, including human and HIV-1 proteases (IC50s = >100 µM for all), as well as a panel of G protein-coupled receptors, kinases, and transporters (IC50s = ≥100 µM for all); inhibits SARS-CoV-2 replication in A549 cells (EC50 = 77.9 nM) and reduces the cytopathic effect of SARS-CoV-2 in infected Vero E6 cells (EC50 = 74.5 nM); reduces lung viral titers and the severity of pulmonary lesions in mice infected with the mouse-adapted SARS-CoV-2 MA10 variant at 300 and 1,000 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
499.526689
产品形式:
A solid
纯度:
≥95%
CAS号:
2628280-40-8
分子式:
C23H32F3N5O4
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