| 货号:AG-CR1-0016-M005 | 规格:5 mg | 目录价:¥780 |
| 货号:AG-CR1-0016-M025 | 规格:25 mg | 目录价:¥2280 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
DAPT
别名:
N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine tert.butyl ester
产品描述:
Cell permeable gamma-secretase inhibitor (IC50 = 115 nM for total beta-amyloid, IC50 = 200 nM for beta-amyloid 1-42) [1]. Reduces Abeta levels in vivo [2]. Blocks the proteolytic processing of neurotrophin receptor alike death domain protein (NRADD) [3]. Does not inhibit persenilinase [4]. Notch processing inhibitor [5]. Enhances neuronal differentiation independent of sonic hedgehog (Shh) signaling [6]. CDK5 activity inhibitor [7]. Apoptosis enhancer [8]. Inhibitor of slurp-like1 expression in the floor plate of the neural tube.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
432.5
产品形式:
solid
产地:
瑞士
纯度:
>98% (NMR)
CAS号:
208255-80-5
分子式:
C23H26F2N2O4
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