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折扣/货期| 货号：SIH-378-5MG | 规格：5 mg | 目录价：￥1339 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
DAPT
别名:
N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine-1,1-dimethylethyl ester
产品描述:
γ-secretase inhibitor
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
432.46
产品形式:
White to off-white powder
产地:
加拿大
功能与背景:
Inhibitor of γ-secretase; causes a reduction in Aβ40 and Aβ42 levels in human primary neuronal cultures (IC50 values are 115 and 200 nM for total Aβ and Aβ42 respectively) and in brain extract, cerebrospinal fluid and plasma in vivo. Does not affect APPα and APPβ levels. Blocks Notch signaling in hybrid human-mouse fetal thymus organ culture (FTOC). Activity causes neural cells to commit to neuronal differentiation.
纯度:
>99%
来源:
Synthetic
CAS号:
208255-80-5
分子式:
C23H26F2N2O4
溶解度:
Soluble to 100 mM in DMSO
PubChem CID:
5311272
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