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折扣/货期| 货号：CHI-HF-210DcR3-C100 | 规格：100 ug | 目录价：￥5390 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
DcR3 (human):Fc (human) (rec.)
别名:
Decoy Receptor 3; Tumor Necrosis Factor Receptor Superfamily Member 6B; TNFRSF6B; M68
产品描述:
Decoy receptor 3 (DcR3; TNFRSF6B; M68) is a member of the TNF receptor superfamily. DcR3 shares sequence identity with OPG (31%), TNF-RII (29%) and Fas (17%) and is expressed in a variety of different tissues and at high levels in many malignant tumors. Ligands of DcR3 include Fas ligand, homologous to lymphotoxin showing inducible expression and competing with HSV glycoprotein D for herpes virus entry mediator (a receptor expressed by T lymphocytes), TNF-like molecule 1A and heparan sulfate proteoglycans. DcR3 modulates the function of T cells, dendritic cells and macrophages. DcR3/Fc fusion proteins can bind to human and mouse B cells and suppress the activation of B cells.
宿主来源:
CHO cells
保存温度:
+4°C
运输温度:
BI
产品形式:
solid
存储溶液:
Lyophilized from 0.2µm-filtered solution in PBS.
产地:
瑞士
纯度:
>98% (SDS-PAGE)
内毒素水平:
<0.06EU/µg protein (LAL test; Lonza).
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