| 货号:9000556-1 mg | 规格:1 mg | 目录价:¥322 |
| 货号:9000556-10 mg | 规格:10 mg | 目录价:¥2318 |
| 货号:9000556-25 mg | 规格:25 mg | 目录价:¥5038 |
| 货号:9000556-5 mg | 规格:5 mg | 目录价:¥1313 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Dimebolin
别名:
Dimebon™|Latrepirdine
产品描述:
A neuroprotective agent; binds to histamine H1 and H2 receptors (IC50s = 3.8 and 287 nM, respectively), as well as α1A-, α1B-, α1D-, and α2A-ARs, imidazoline I2 receptors, and 5-HT2A, 5-HT2C, 5-HT6, and 5-HT7 receptors (Kis = 8-313 nM); inhibits NMDA-evoked currents and voltage-gated calcium channels in mouse primary striatal neurons (IC50s = 10 and 50 μM, respectively); inhibits glutamate-induced apoptosis in primary striatal neurons derived from the YAC128 transgenic mouse model of Huntington’s disease at 50 μM; inhibits cell death induced by amyloid-β (25-35) in cerebellar granule cells at 25 μM; inhibits decreases TWAA acquisition in a rat model of AF64A-induced Alzheimer’s disease at 1 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
319.4
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
3613-73-8
分子式:
C21H25N3
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