| 货号:9000554-10 mg | 规格:10 mg | 目录价:¥2332 |
| 货号:9000554-25 mg | 规格:25 mg | 目录价:¥5199 |
| 货号:9000554-5 mg | 规格:5 mg | 目录价:¥1260 |
| 货号:9000554-50 mg | 规格:50 mg | 目录价:¥7692 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Riociguat
别名:
BAY 63-2521
产品描述:
A stimulator of sGC; stimulates recombinant sGC in a concentration-dependent manner in vitro by up to 73-fold at 100 μM or by up to 112-fold when used in combination with DEA NONOate; has no effect on phosphodiesterases PDE1-9 and PDE11 at ≤3 μM; reduces pulmonary and systemic arterial pressure at 1 and 10 mg/kg in a rabbit model of acute PAH induced by U-46619; inhibits increases in right ventricular systolic pressure, right heart hypertrophy, and pulmonary artery muscularization in hypoxia-induced mouse and monocrotaline-injected rat models of chronic PAH at 10 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
422.4
产品形式:
A crystalline solid
纯度:
≥98%
CAS号:
625115-55-1
分子式:
C20H19FN8O2
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