| 货号:AG-40A-0107Y-3010 | 规格:3 x 10 ug | 目录价:¥5760 |
| 货号:AG-40A-0107Y-C010 | 规格:10 ug | 目录价:¥2880 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
DLK1 (mouse):Fc (human) (rec.)
别名:
Protein Delta Homolog 1; Fetal Antigen 1; Preadipocyte Factor 1; Pref-1; FA1
产品描述:
The transmembrane and secreted protein delta-like 1 homolog (DLK1; Protein delta homolog 1; Preadipocyte factor 1; Pref-1) belongs to the EGF-like family. It can be cleaved by a tumor necrosis factor-alpha converting enzyme (TACE) to release a soluble form. DLK1 plays important roles in regulating cell differentiation such as adipogenesis and osteogenesis. Membrane-bound DLK1 promotes hypertrophic myotube formation, whereas soluble DLK1 inhibits myotube formation. The soluble form of DLK1 inhibits preadipocyte differentiation, while membrane DLK1 represses preadipocyte proliferation. DLK1 is also associated with tumor invasion.
宿主来源:
HEK 293 cells
产品浓度:
0.1mg/ml after reconstitution
保存温度:
+4°C
运输温度:
BI
预期分子量:
~75kDa (SDS-PAGE)
产品形式:
solid
存储溶液:
Lyophilized. Contains PBS + 0.02% CHAPS.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
生物活性:
Inhibits adipogenesis of 3T3L-1 cells. Induces Sox-9 in 3T3L-1 cells.
内毒素水平:
<0.1EU/µg purified protein (LAL test; Lonza).
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