| 货号:AG-40B-0176-C010 | 规格:10 ug | 目录价:¥3600 |
| 货号:AG-40B-0176-C100 | 规格:100 ug | 目录价:¥11400 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
DLL4 (human):Fc (human) (rec.) (highly active mutant)
别名:
Delta-like Protein 4; Delta4
产品描述:
The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, promoting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.
宿主来源:
HEK 293 cells
靶标/特异性:
Interacts with human and mouse Notch1 with >20 fold increase in affinity relative to WT DLL4 (as confirmed by ELISA).
产品浓度:
After reconstitution:for 10µg size: 0.1mg/mlfor 100µg size: 1 mg/ml
保存温度:
+4°C
运输温度:
BI
预期分子量:
~100kDa (SDS-PAGE)
产品形式:
solid
存储溶液:
Lyophilized. Contains PBS.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
内毒素水平:
<0.01EU/µg purified protein (LAL test).
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