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折扣/货期| 货号：V4009-100UG | 规格：100 ug | 目录价：￥6652.1 |
| 货号：V4009-20UG | 规格：20 ug | 目录价：￥3082.1 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
DMD Antibody / Dystrophin
产品描述:
Dystrophin-glycoprotein complex (DGC) connects the F-Actin cytoskeleton on the inner surface of muscle fibers to the surrounding extracellular matrix, through the cell membrane interface. A deficiency in this protein contributes to Duchenne (DMD) and Becker (BMD) muscular dystrophies. The human dystrophin gene measures 2.4 megabases, has more than 80 exons, produces a 14 kb mRNA and contains at least 8 independent tissue-specific promoters and 2 poly A sites. The dystrophin mRNA can undergo differential splicing and produce a range of transcripts that encode a large set of proteins. Dystrophin represents approximately 0.002% of total striated muscle protein and localizes to triadic junctions in skeletal muscle, where it is thought to influence calcium ion homeostasis and force transmission.
反应种属:
Human
宿主来源:
Mouse
实验应用:
IF, WB, IHC-P
同种型:
Mouse IgG2a, kappa
免疫原:
A portion of amino acids 1700-2300 from the human Dystrophin was used as the immunogen for the DMD antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
DMD/6270
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the DMD antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
产地:
美国
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