官网链接
折扣/货期| 货号：V3827-100UG | 规格：100 ug | 目录价：￥6652.1 |
| 货号：V3827-20UG | 规格：20 ug | 目录价：￥3082.1 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Dnmt3a Antibody
产品描述:
DNMT3A is required for genome-wide de novo methylation and is essential for the establishment of DNA methylation patterns during development. DNA methylation is coordinated with methylation of histones. It modifies DNA in a non-processive manner and also methylates non-CpG sites. May preferentially methylate DNA linker between 2 nucleosomal cores and is inhibited by histone H1. Plays a role in paternal and maternal imprinting. Required for methylation of most imprinted loci in germ cells. Acts as a transcriptional corepressor for ZBTB18. Recruited to trimethylated 'Lys-36' of histone H3 (H3K36me3) sites. Can actively repress transcription through the recruitment of HDAC activity.
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P, WB
同种型:
Mouse IgG1, kappa
免疫原:
Recombinant full length human protein was used as the immunogen for this Dnmt3a antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
PCRP-DNMT3A-1E2
纯化方式:
Protein G affinity chromatography
保存温度:
Store the Dnmt3a antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
产品形式:
Purified
存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
产地:
美国
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