深圳欣博盛生物科技有限公司 a1

DO264
货号:29402-1 mg 规格:1 mg 目录价:¥1085
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
DO264
产品描述:
An ABHD12 inhibitor (IC50 = 11 nM); inhibits ABHD-dependent hydrolysis of lyso-PS in mouse brain membrane lysates (IC50 = 2.8 nM) and human THP-1 cells; increases levels of CCL3, CCL4, TNF-α, and IL-1β in M1-polarized THP-1 macrophages; increases levels of 1-stearoyl-2-hydroxy-sn-glycero-3-PS, 1-arachidonoyl-2-hydroxy-sn-glycero-3-PS, 1-docosanoyl-2-hydroxy-sn-glycero-3-PS, 1-stearoyl-2-arachidonoyl-sn-glycero-3-PS, and 1-oleoyl-2-arachidonoyl-sn-glycero-3-PS in mouse brain at 30 mg/kg per day for four weeks; increases levels of CCL2, CCL3, and CCL5 in BALF and decreases survival in a mouse model of infection with LCMV clone 13 at 30 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
558.404009
产品形式:
A solid
纯度:
≥98%
CAS号:
2301866-59-9
分子式:
C23H20Cl2F3N5O2S
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