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折扣/货期| 货号：GTX28450 | 规格：50μg | 目录价：￥2400 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
DR6 peptide
别名:
Tnf Receptor Superfamily Member 21 , Bm-018 , Cd358 , Dr6 , Tnfrsf21
实验应用:
Neutralizing/Inhibition
克隆号:
偶联:
Unconjugated
产品浓度:
0.20 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store the peptide at -20ºC, stable for one year.
运输温度:
dry ice
产品形式:
Liquid
存储溶液:
PBS, 0.1% BSA, 0.02% Sodium azide.
生产商:
GeneTex
功能与背景:
Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. Several novel death receptors including DR3, DR4, and DR5 were recently identified. A new death domain containing receptor in the TNFR family was cloned recently and termed DR6 for death receptor 6. Like TNFR1, DR6 interacts with death domain containing adapter molecule TRADD. Overexpression of DR6 induces apoptosis and activates NF-kB and JNK. DR6 is widely expressed inhuman tissues and cell lines. The ligand for DR6 hasnot been identified.
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