DUX4 Antibody-单抗-深圳欣博盛生物科技有限公司

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DUX4 Antibody

品牌：Stressmarq

官网链接

说明书

折扣/货期

货号：SMC-192D

规格：100 µg

目录价：￥4246.2

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

DUX4 Antibody

别名:

Double homeobox 4 Antibody, Double homeobox 10 Antibody, DUX10 Antibody, Double homeobox protein 4/10 Antibody, DUX4L antibody, DUX4L1 antibody

产品描述:

Mouse Anti-Human DUX4 Monoclonal IgG1

反应种属:

Human | Mouse

宿主来源:

Mouse

实验应用:

WB | IHC | ICC/IF

靶标/特异性:

Detects ~45kDa. No cross-reactivity with DUX4c.

同种型:

IgG1

推荐稀释度:

WB (1:1000), ICC/IF (1:1000); optimal dilutions for assays should be determined by the user.

免疫原:

C-terminal 76 amino acids of Human DUX4 with glutathione-s-transferase (gst) tag

免疫原种属:

Human

克隆性:

Monoclonal

克隆号:

P2B1

纯化方式:

Protein G Purified

偶联:

Unconjugated

产品浓度:

1 mg/ml

保存温度:

-20ºC

运输温度:

Blue Ice or 4ºC

存储溶液:

PBS pH7.4, 50% glycerol, 0.09% sodium azide *Storage buffer may change when conjugated

产地:

加拿大

功能与背景:

DUX4, or double homeobox4, is a human protein that is a transcriptional activator of paired-like homeodomain transcription factor 1 (1). Clinically it is a facioscapulohumeral muscular dystrophy candidate gene that appears to have a toxic gain of function (2-4). In FSHD individuals, the expression of the full-length DUX4 transcript is not completely suppressed in skeletal muscle and possibly other differentiated tissues (5).

Accession #:

NP_149418.3