E2F4 antibody-多抗-深圳欣博盛生物科技有限公司

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E2F4 antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX134346	规格：100μl	目录价：￥4000
货号：GTX134346-S	规格：25μl	目录价：￥1700

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

E2F4 antibody

别名:

E2F transcription factor 4 , E2F-4

反应种属:

Human

宿主来源:

Rabbit

实验应用:

靶标/特异性:

E2F4

同种型:

IgG

免疫原:

Recombinant protein encompassing a sequence within the center region of human E2F4. The exact sequence is proprietary.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by antigen-affinity chromatography.

偶联:

Unconjugated

产品浓度:

2.4 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

预期分子量:

产品形式:

Liquid

存储溶液:

PBS, 20% Glycerol, 0.025% ProClin 300.

生产商:

GeneTex

功能与背景:

The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein binds to all three of the tumor suppressor proteins pRB, p107 and p130, but with higher affinity to the last two. It plays an important role in the suppression of proliferation-associated genes, and its gene mutation and increased expression may be associated with human cancer. [provided by RefSeq, Jul 2008]

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