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折扣/货期| 货号：V4441SAF-100UG | 规格：100 ug | 目录价：￥6652.1 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
E2F4 Antibody
产品描述:
The human retinoblastoma gene product appears to play an important role in the negative regulation of cell proliferation. Functional inactivation of Rb can be mediated either through mutation or as a consequence of interaction with DNA tumor virus-encoded proteins. Of all the Rb associations described to date, the identification of a complex between Rb and the transcription factor E2F most directly implicates Rb in regulation of cell proliferation. E2F was originally identified through its role in transcriptional activation of the adenovirus E2 promoter. Sequences homologous to the E2F binding site have been found upstream of a number of genes that encode proteins with putative functions in the G1 and S phases of the cell cycle. E2F-1 is a member of a broader family of transcription regulators including E2F-2, E2F-3, E2F-4, E2F-5, E2F-6 and E2F-7 each of which forms heterodimers with a second protein, DP-1, forming an active E2F transcriptional regulatory complex.
反应种属:
Human
宿主来源:
Rabbit
实验应用:
IHC-P
同种型:
Rabbit IgG, kappa
免疫原:
A recombinant partial protein sequence (within amino acids 1-100) from the human protein was used as the immunogen for the E2F4 antibody.
克隆性:
Recombinant Rabbit Monoclonal
克隆号:
E2F4/8984R
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the E2F4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
1 mg/ml in 1X PBS; BSA free, sodium azide free
产地:
美国
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