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折扣/货期| 货号：37296-1 mg | 规格：1 mg | 目录价：￥1112 |
| 货号：37296-10 mg | 规格：10 mg | 目录价：￥5534 |
| 货号：37296-25 mg | 规格：25 mg | 目录价：￥11055 |
| 货号：37296-5 mg | 规格：5 mg | 目录价：￥3605 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
E6446 (hydrochloride)
产品描述:
A TLR7 and TLR9 antagonist (IC50s = 1.78 and 0.01 µM, respectively); selective for TLR7 and TLR9 over TLR4 (IC50 = 10.58 µM); inhibits CpG ODN2216- or RNA40-induced IL-6 production in isolated mouse BMDCs; prevents increases in left ventricle chamber size and cardiac fibrosis in a mouse model of transverse aortic constriction-induced heart failure at 1.5 mg/animal; increases survival and reduces increases in right ventricular systolic pressure and hypertrophy in a rat model of monocrotaline-induced pulmonary hypertension at 10 mg/kg; has been used to enhance the transfection efficiency of cell-penetrating peptides for the delivery of mRNA in vitro
保存温度:
-20
运输温度:
-20
预期分子量:
449.58522
产品形式:
A solid
纯度:
≥95%
CAS号:
1345675-25-3
分子式:
C27H35N3O3 • 2HCl
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