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折扣/货期| 货号：37297-1 mg | 规格：1 mg | 目录价：￥589.6 |
| 货号：37297-10 mg | 规格：10 mg | 目录价：￥2907.8 |
| 货号：37297-25 mg | 规格：25 mg | 目录价：￥6592.8 |
| 货号：37297-5 mg | 规格：5 mg | 目录价：￥1594.6 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Trilaciclib (hydrochloride)
别名:
G1T28
产品描述:
An inhibitor of Cdk4 and Cdk6 (IC50s = 1 and 4 nM, respectively); selective for Cdk4/cyclin D1 and Cdk6/cyclin D3 over Cdk2/cyclin A, Cdk2/cyclin E, Cdk5/p25, Cdk5/p35, Cdk7/cyclin H/Mat1, and Cdk9/cyclin T (IC50s = 50-4,640 nM); halts the cell cycle at the G1 phase in Cdk4/6-dependent Hs68 cells (EC50 = 30 nM); prevents camptothecin-induced DNA damage and apoptosis in Hs68 cells at 10-1,000 nM; induces reversible cell cycle arrest of HSPCs in mice at 50, 100, or 150 mg/kg; prevents etoposide-induced apoptosis of bone marrow cells in mice at 100 mg/kg; prevents 5-FU-induced myelosuppression in mice at 150 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
519.4696
产品形式:
A solid
有效期:
1460
纯度:
≥98%
CAS号:
1977495-97-8
分子式:
C24H30N8O • 2HCl
促销活动
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