EGF receptor Recombinant Protein-细胞因子、趋化因子与生长因子-深圳欣博盛生物科技有限公司

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EGF receptor Recombinant Protein

品牌：ProSci LLC

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说明书

折扣/货期

货号：40-516-0.002 mg	规格：0.002 mg	目录价：￥3783
货号：40-516-0.01 mg	规格：0.01 mg	目录价：￥5674.5

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

EGF receptor Recombinant Protein

别名:

ERBB, HER1, mENA, ERBB1, PIG61, ERBB, Epidermal growth factor receptor, Proto-oncogene c-ErbB-1

表达系统:

CHO cells

保存温度:

The lyophilized EGF receptor recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted EGF receptor is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing EGF receptor recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

运输温度:

Blue Ice

产品形式:

Lyophilized

产地:

美国

生产商:

Prosci

功能与背景:

EGF Receptor (EGFR, ErbB1) is a transmembrane protein that exerts tyrosine kinase activity upon ligand induced activation. EGFR can be activated by binding EGF or at least six other structurally related protein ligands, including TGF, HB-EGF, Betacellulin (BTC), Amphiregulin, Epiregulin, and Epigen. Upon activation, EGFR initiates a signaling cascade which includes dimerization and internalization, tyrosine phosphorylation, DNA synthesis of target genes, and, ultimately, cell proliferation. EGFR signaling plays a role in the growth and differentiation of normal cells, but elevated EGFR activity is correlated with the development and pathogenesis of certain cancers. Recombinant soluble human EGFR is a 621 amino acid glycoprotein comprising the extracellular domain of EGFR, and migrates at an apparent MW of 97.5 kDa by SDS-PAGE analysis under reducing conditions.

纯度:

Greater than or equal to 95% by SDS-PAGE gel and HPLC analyses.

生物活性:

Endotoxin level is less than 0.1 ng per μg (1EU/μg).

Accession #:

NP_005219.2

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