| 货号:36227-10 mg | 规格:10 mg | 目录价:¥724 |
| 货号:36227-25 mg | 规格:25 mg | 目录价:¥1715 |
| 货号:36227-5 mg | 规格:5 mg | 目录价:¥389 |
| 货号:36227-50 mg | 规格:50 mg | 目录价:¥3015 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Eleclazine
别名:
Dihydrobenzoxazepinone|GS-6615
产品描述:
An inhibitor of the cardiac late INa (IC50 = 0.88 µM in HEK293 cells expressing the α subunit of Nav1.5); selective for the cardiac late INa over a panel of 11 cardiac ion channels at 1 µM, as well as Nav1.1-1.4 and Nav1.6-1.8 (IC50s = ≥5 µM for all); reverses anemone toxin-II-induced activation of MAPD90 in isolated rabbit hearts (EC50 = 0.72 µM); inhibits S-T segment elevation in a rabbit model of cardiac ischemia-reperfusion injury induced by occlusion of the left anterior descending artery (EC50 = 0.19 µM); decreases the incidence of ventricular tachycardia-ventricular fibrillation and mortality in a rabbit model of ischemia-induced arrhythmia induced by left circumflex artery ligation
保存温度:
-20
运输温度:
-20
预期分子量:
415.365369
产品形式:
A solid
纯度:
≥98%
CAS号:
1443211-72-0
分子式:
C21H16F3N3O3
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