官网链接
折扣/货期| 货号：36226-10 mg | 规格：10 mg | 目录价：￥925 |
| 货号：36226-25 mg | 规格：25 mg | 目录价：￥1595 |
| 货号：36226-5 mg | 规格：5 mg | 目录价：￥536 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Flumatinib
别名:
HH-GV-678
产品描述:
A Bcr-Abl inhibitor (IC50 = 1.2 nM); selective for Bcr-Abl over VEGFR2, c-Src, EGFR, and HER2 at 1 µM but does inhibit PDGFRβ and c-Kit (IC50s = 307.6 and 665.5 nM, respectively); inhibits the proliferation of K562 cells expressing wild-type Bcr-Abl (IC50 = 5.1 nM) and 32D cells expressing the Bcr-Abl mutations Bcr-AblQ252H, Bcr-AblY253F, Bcr-AblE255K, Bcr-AblM351T, and Bcr-AblH396P (IC50s = 76.3, 40.4, 123.2, 20.2, and 34.6 nM, respectively), which are resistant to imatinib; induces tumor regression and increases survival time in a K562 mouse xenograft model at 75 mg/kg per day; increases the viability of SARS-CoV-2-infected Vero E6 cells (EC50 = 1.6 µM)
保存温度:
-20
运输温度:
-20
预期分子量:
562.589089
产品形式:
A solid
纯度:
≥98%
CAS号:
895519-90-1
分子式:
C29H29F3N8O
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