官网链接
折扣/货期| 货号：43585-1 mg | 规格：1 mg | 目录价：￥871 |
| 货号：43585-10 mg | 规格：10 mg | 目录价：￥4797 |
| 货号：43585-25 mg | 规格：25 mg | 目录价：￥8697 |
| 货号：43585-5 mg | 规格：5 mg | 目录价：￥3926 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Eltanexor
别名:
KPT-8602
产品描述:
An inhibitor of XPO1/CRM1; inhibits the binding of XPO1/CRM1 to various NESs in cell-free pull-down assays at 10 µM; inhibits Cas9-encoding mRNA nuclear export in HEK293T cells; inhibits CRISPR-Cas9 gene editing in a reporter assay using HEK293 cells (IC50 = 94 nM); inhibits human CMV replication in primary human foreskin fibroblasts (IC50 = 37.62 nM); induces IκBα and NF-κB p65 nuclear accumulation and inhibits RANKL-induced osteoclast differentiation in isolated mouse BMDMs at 100 nM; induces apoptosis in primary human CLL cells and increases survival and decreases spleen leukemic burden in an MV4-11 AML mouse xenograft model; increases locomotor activity and tibialis anterior myofiber size and decreases serum OPN levels in the D2-mdx mouse model of DMD at 5 mg/kg five times per week
保存温度:
-20
运输温度:
-20
预期分子量:
428.298419
产品形式:
A solid
纯度:
≥98%
CAS号:
1642300-52-4
分子式:
C17H10F6N6O
促销活动
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