| 货号:43576-10 mg | 规格:10 mg | 目录价:¥2787 |
| 货号:43576-25 mg | 规格:25 mg | 目录价:¥5816 |
| 货号:43576-5 mg | 规格:5 mg | 目录价:¥1554 |
| 货号:43576-50 mg | 规格:50 mg | 目录价:¥9286 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
GW 8510
产品描述:
A Cdk2 and Cdk5 inhibitor (IC50s = 3, 3, and 7 nM for Cdk2/cyclin E, Cdk2/cyclin A, and Cdk5/p25 complexes, respectively); selective for Cdk2 and Cdk5 over Cdk1/cyclin B, Cdk4/cyclin D, Cdk7/cyclin H, and Cdk9/cyclin T (IC50s = 49, 139, 317, and 543 nM, respectively); decreases RRM2 levels and induces autophagy in HCT116 cells at 4 µM; protects against MPP+-induced cytotoxicity in primary human neural progenitor cells derived from iPSCs in an in vitro model of Parkinson’s disease from 1-500 nM; increases grip strength and gastrocnemius and soleus muscle-to-body weight ratios in a mouse model of muscle atrophy induced by sciatic nerve denervation at 2 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
449.503
产品形式:
A solid
纯度:
≥98%
CAS号:
222036-17-1
分子式:
C21H15N5O3S2
促销活动
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官网链接
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