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折扣/货期| 货号：GTX30618 | 规格：100μg | 目录价：￥6100 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
EP300 antibody [RW105]
别名:
E1A binding protein p300 , KAT3B , MKHK2 , RSTS2 , p300
反应种属:
Human, Mouse, Mustelid, Primate, Rat
宿主来源:
Mouse
实验应用:
ChIP assay, EM, FCM, ICC/IF, in vitro, IP, WB
靶标/特异性:
This is specific for p300 protein. This recognizes residues 1921-2023.
同种型:
IgG1
免疫原:
Fusion protein containing residues 1572-2371 of human KAT3B/p300. [UniProt# Q0947]
克隆性:
Monoclonal
克隆号:
RW105
纯化方式:
Protein G purified
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
264
产品形式:
Liquid
存储溶液:
PBS, 0.1% Sodium azide.
生产商:
GeneTex
功能与背景:
This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq]
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