| 货号:F54127-0.05ML | 规格:0.05 ml | 目录价:¥2962.25 |
| 货号:F54127-0.2ML | 规格:0.2 ml | 目录价:¥6343.55 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
ERAB Antibody / HSD17B10 (N-Terminal Region)
产品描述:
ERAB / HSD17B10 functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD). [UniProt]
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB
同种型:
Rabbit Ig
免疫原:
A portion of amino acids 14-48 from human ERAB was used as the immunogen for the ERAB antibody.
克隆性:
Polyclonal (rabbit origin)
纯化方式:
Antigen affinity
保存温度:
Aliquot the ERAB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Antigen affinity purified
存储溶液:
In 1X PBS, pH 7.4, with 0.09% sodium azide
产地:
美国
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