官网链接
折扣/货期| 货号：GTX89421-PEP | 规格：100μg | 目录价：￥3200 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
ERG blocking peptide
别名:
Ets Transcription Factor Erg , Erg-3 , P55 , Erg
靶标/特异性:
The peptide was used in the production of GTX89421.
克隆号:
产品浓度:
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Lyophilized powder
存储溶液:
Reconstitute with 200μl distilled water to obtain a 0.5mg/ml peptide solution. Lyophilized from 5% (v/v) acetonitrile/H₂O, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the erythroblast transformation-specific (ETS) family of transcriptions factors. All members of this family are key regulators of embryonic development, cell proliferation, differentiation, angiogenesis, inflammation, and apoptosis. The protein encoded by this gene is mainly expressed in the nucleus. It contains an ETS DNA-binding domain and a PNT (pointed) domain which is implicated in the self-association of chimeric oncoproteins. This protein is required for platelet adhesion to the subendothelium, inducing vascular cell remodeling. It also regulates hematopoesis, and the differentiation and maturation of megakaryocytic cells. This gene is involved in chromosomal translocations, resulting in different fusion gene products, such as TMPSSR2-ERG and NDRG1-ERG in prostate cancer, EWS-ERG in Ewing's sarcoma and FUS-ERG in acute myeloid leukemia. More than two dozens of transcript variants generated from combinatorial usage of three alternative promoters and multiple alternative splicing events have been reported, but the full-length nature of many of these variants has not been determined. [provided by RefSeq, Apr 2014]
您可能感兴趣的产品
ARFGAP1 Blocking Peptide
货号：33R-9999
Carbonic Anhydrase Vb Blocking Peptide (Mitochondrial)
货号：33R-9998
FBXL14 Blocking Peptide
货号：33R-9997
TMEM149 Blocking Peptide
货号：33R-9996
PLEKHH2 Blocking Peptide
货号：33R-9995
NECAP2 Blocking Peptide
货号：33R-9994
LARP7 Blocking Peptide
货号：33R-9993
UBE2L3 Blocking Peptide
货号：33R-9992
促销活动
精品推荐
复制QQ号成功，请打开QQ后添加好友进行咨询