ERK2 Antibody / MAPK1-单抗-深圳欣博盛生物科技有限公司

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ERK2 Antibody / MAPK1

品牌：NSJ Bio

官网链接

说明书

折扣/货期

货号：V9723-100UG	规格：100 ug	目录价：￥6414.1
货号：V9723-20UG	规格：20 ug	目录价：￥2963.1

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

ERK2 Antibody / MAPK1

产品描述:

Mitogen-activated protein kinase (MAPK) signaling pathways involve two closely-related MAP kinases, known as extracellular-signal-related kinase 1 (ERK 1, p44) and 2 (ERK 2, p42). Growth factors, steroid hormones, G protein coupled receptor ligands and neurotransmitters can initiate MAPK signaling pathways. Activation of ERK 1 and ERK 2 requires phosphorylation by upstream kinases such as MAP kinase (MEK), MEK kinase and Raf-1. ERK 1 and ERK 2 phosphorylation can occur at specific tyrosine and threonine sites mapping within consensus motifs that include the threonine-glutamate-tyrosine motif. ERK activation leads to dimerization with other ERKs and subsequent localization to the nucleus. Active ERK dimers phosphorylate serine and threonine residues on nuclear proteins and influence a host of responses that include proliferation, differentiation, transcription regulation and development.

反应种属:

Human

宿主来源:

Mouse

实验应用:

ELISA, FACS, IF

同种型:

Mouse IgG2b

免疫原:

Recombinant full-length human protein was used as the immunogen for the ERK2 antibody.

克隆性:

Monoclonal (mouse origin)