官网链接
折扣/货期| 货号：V9723-100UG | 规格：100 ug | 目录价：￥6652.1 |
| 货号：V9723-20UG | 规格：20 ug | 目录价：￥3082.1 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
ERK2 Antibody / MAPK1
产品描述:
Mitogen-activated protein kinase (MAPK) signaling pathways involve two closely-related MAP kinases, known as extracellular-signal-related kinase 1 (ERK 1, p44) and 2 (ERK 2, p42). Growth factors, steroid hormones, G protein coupled receptor ligands and neurotransmitters can initiate MAPK signaling pathways. Activation of ERK 1 and ERK 2 requires phosphorylation by upstream kinases such as MAP kinase (MEK), MEK kinase and Raf-1. ERK 1 and ERK 2 phosphorylation can occur at specific tyrosine and threonine sites mapping within consensus motifs that include the threonine-glutamate-tyrosine motif. ERK activation leads to dimerization with other ERKs and subsequent localization to the nucleus. Active ERK dimers phosphorylate serine and threonine residues on nuclear proteins and influence a host of responses that include proliferation, differentiation, transcription regulation and development.
反应种属:
Human
宿主来源:
Mouse
实验应用:
ELISA, FACS, IF
同种型:
Mouse IgG2b
免疫原:
Recombinant full-length human protein was used as the immunogen for the ERK2 antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
PCRP-MAPK1-1D1
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the ERK2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
产地:
美国
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