Etoposide-抑制剂-深圳欣博盛生物科技有限公司

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Etoposide

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-CR1-3572-5100	规格：5 x 100 mg	目录价：￥3120
货号：AG-CR1-3572-M025	规格：25 mg	目录价：￥300
货号：AG-CR1-3572-M100	规格：100 mg	目录价：￥780

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Etoposide

别名:

VP-16-213; NSC 141540

产品描述:

Potent anti-cancer compound. Induces apoptosis in normal and tumor cell lines [1, 5]. DNA Topoisomerase II activity inhibitor. Increases Topo II-mediated DNA breakage primarily by inhibiting the ability of the enzyme to religate cleaved nucleic acid molecules. Does not lead to immediate block of DNS synthesis, induces a progressive inhibition of DNA replication [2, 4, 6]. p53 activator [3]. Blocks the cell cycle between the end of the S phase and the early G2 phase [2, 8]. Oncoprotein Mdm2 synthesis inhibitor [7]. Apoptosis inducer through the cytochrome c/Apaf-1/caspase-9 pathway and the Fas-mediated death signaling pathway [9, 10]. Cell cycle checkpoint activator. Affects gene expression at different levels (chromatin remodeling, transcription and alternative splicing) [11, 14, 15]. Chemotherapeutic compound used in cancers [12, 13]. Used in conditioning regimen prior to a bone marrow or blood stem cell transplantation [16]. Highly effective in mobilizing stem cells [17]

宿主来源:

Semisynthetic derivative of podophyllotoxin.

保存温度:

+20°C

运输温度:

Ambient

预期分子量:

588.6

产品形式:

solid

产地:

瑞士