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折扣/货期| 货号：GTX30142 | 规格：50μl | 目录价：￥7000 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
FANCD2 antibody
别名:
FA complementation group D2 , FA-D2 , FA4 , FACD , FAD , FAD2 , FANCD
反应种属:
Dog, Human, Mouse, Primate
宿主来源:
Rabbit
实验应用:
FCM, IHC-P, IP, WB
靶标/特异性:
This antibody is specific for FANCD2.
同种型:
IgG
免疫原:
Human FANCD2 fusion protein (N-terminal fragment). [Swiss-Prot #Q9BXW9]
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by antigen-affinity chromatography
偶联:
Unconjugated
产品浓度:
1 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
164
产品形式:
Liquid
存储溶液:
PBS, 0.05% Sodium azide.
生产商:
GeneTex
功能与背景:
The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq]
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