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折扣/货期| 货号：AG-35B-0018-C050 | 规格：50 ug | 目录价：￥3600 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Fc (LALA-PG)-KIH (human) IgG1 Control (rec.)
别名:
Fc (LALA-PG) Knobs-into-Holes (human) IgG1; Immunoglobulin 1 Fragment Constant
产品描述:
Negative control in experiments with recombinant proteins fused to human IgG1 Fc (LALA-PG)-KIH (Knobs-into-Holes) (e.g. Prod. No. AG-40B-0248). This protein is not an appropriate negative control for other standard Fc protein constructs. The protein Fc (LALA-PG)-KIH (human) IgG1 Control (rec.) is produced by using two different vectors, one encoding for the Fc (LALA-PG) Knobs sequence with a small linker (synthesizing a protein of 29kDa) and one encoding for the Fc (LALA-PG) Holes sequence (synthesizing a protein of 28kDa). Both vectors transfected into HEK293 cells produce both Fc molecules (Knobs-into-Holes technology; J.B. Ridgway, et al.; Protein Eng. 9, 617 (1996)) required for dimerization and for secretion of the final protein Fc (LALA-PG)-KIH (human) IgG1 Control (rec.). The Fc contains the mutations LALA-PG that abolish the interaction between the Fc and FcgammaRs and therefore Fc undesirable effects. InVivoKines™ are a new generation of recombinant fusion proteins for immunotherapeutic, preclinical and translational in vivo research, developed and manufactured by AdipoGen Life Sciences.
宿主来源:
HEK 293 cells
靶标/特异性:
Fc (LALA-PG)-KIH (human) does not bind to FcRs.
产品浓度:
After reconstitution: 1mg/ml
保存温度:
+4°C
运输温度:
BI
预期分子量:
~28kDa (SDS-PAGE)
产品形式:
solid
存储溶液:
Lyophilized. Contains PBS.
有效期:
Stable for at least 6 months after receipt when stored at -20°C.Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>95% (SDS-PAGE)
内毒素水平:
<0.01EU/µg purified protein (LAL test).
促销活动
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