UBE2L3 [UbcH7] (human) (rec.) (untagged)-其他重组蛋白-深圳欣博盛生物科技有限公司

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UBE2L3 [UbcH7] (human) (rec.) (untagged)

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：SBB-CE0020-C100

规格：100 ug

目录价：￥4032

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

UBE2L3 [UbcH7] (human) (rec.) (untagged)

别名:

Ubiquitin-conjugating Enzyme E2 L3; E2-F1; L-UBC; UBCE7; UbcM4; UBE2L3; Ubiquitin-protein Ligase L3

产品描述:

UBE2L3 (UbcH7) is an E2 ubiquitin conjugating enzyme and accepts ubiquitin from an E1 activating enzyme via an active site cysteine. The mechanism of ubiquitin transfer involves the breaking of a E1-Ub thioester linkage, followed by a reformation of a UBE2L3-Ub thioester. UBE2L3 transfers active ubiquitin molecules via a final transthiolation reaction to a cysteine residue of HECT class or RBR class E3 ligases. UBE2L3 plays a critical role in the activation of NF-kappab signaling by working in conjugation with the RBR E3 ligase, LUBAC (linear ubiquitin assembly complex), to ubiquitinate NEMO of the IkappaB complex, which than facilitates the downstream immune response.

宿主来源:

E. coli

产品浓度:

Lot dependent.

保存温度:

-80°C

运输温度:

Dry Ice

预期分子量:

~18kDa

产品形式:

liquid