| 货号:GTX637074 | 规格:100μl | 目录价:¥4000 |
| 货号:GTX637074-S | 规格:25μl | 目录价:¥1700 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
FGFR3 antibody [HL1595]
别名:
fibroblast growth factor receptor 3 , ACH , CD333 , CEK2 , HSFGFR3EX , JTK4
反应种属:
Cat, Dog, Human
宿主来源:
Rabbit
实验应用:
WB
靶标/特异性:
This antibody was raised against human FGFR3 Intracellular domain.
同种型:
IgG
免疫原:
Synthetic peptide encompassing a sequence within the Intracellular domain of human FGFR3. The exact sequence is proprietary.
克隆性:
Monoclonal
克隆号:
HL1595
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
2 mg/ml (Please refer to the vial label for the specific concentration.)
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. [provided by RefSeq, Aug 2017]
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