| 货号:GTX642486 | 规格:100μl | 目录价:¥4000 |
| 货号:GTX642486-S | 规格:25μl | 目录价:¥1700 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
FIG4 antibody [GT149]
别名:
FIG4 phosphoinositide 5-phosphatase , ALS11 , BTOP , CMT4J , KIAA0274 , SAC3 , YVS , dJ249I4.1
反应种属:
Human, Mouse, Rat
宿主来源:
Mouse
实验应用:
WB
同种型:
IgG2b
免疫原:
The immunogen used to generate this antibody corresponds to human FIG4.
克隆性:
Monoclonal
克隆号:
GT149
纯化方式:
Affinity purified by Protein A.
偶联:
Unconjugated
产品浓度:
1 mg/ml
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
产品形式:
Liquid
存储溶液:
PBS, no preservatives.
生产商:
GeneTex
功能与背景:
The protein encoded by this gene belongs to the SAC domain-containing protein gene family. The SAC domain, approximately 400 amino acids in length and consisting of seven conserved motifs, has been shown to possess phosphoinositide phosphatase activity. The yeast homolog, Sac1p, is involved in the regulation of various phosphoinositides, and affects diverse cellular functions such as actin cytoskeleton organization, Golgi function, and maintenance of vacuole morphology. Membrane-bound phosphoinositides function as signaling molecules and play a key role in vesicle trafficking in eukaryotic cells. Mutations in this gene have been associated with Charcot-Marie-Tooth disease, type 4J. [provided by RefSeq, Jul 2008]
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