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折扣/货期| 货号：SIH-214-10MG | 规格：10 mg | 目录价：￥1411.2 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
FK506
别名:
3-(3-Pyridinyl)propyl 1-(3,3-dimethyl-2-oxopentanoyl)prolinate, Tacrolimus, Fujimycin
产品描述:
FKBP inhibitor
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
804
产品形式:
White powder
产地:
加拿大
功能与背景:
FK506 or Fujimycin or Tacrolimus, is an immunosuppressant. It is mainly used after allogeneic organ transplants, but can also be used topically in the treatment of eczema, uveitis and vitiligo (1). It is a macrolide that prevents the dephosphorylation of NF-AT. It reduces peptidyl-prolyl isomerase activity by binding to FKBP12 creating a new complex that interacts with and inhibits calcineurin (2, 3). It is a neuroprotective in a model of antiretroviral toxic neuropathy (4).
纯度:
>98%
来源:
Synthetic
CAS号:
104987-11-3
分子式:
C44H69HO12
溶解度:
May be dissolved in DMSO (50 mg/mL) or ethanol (50mg/mL)
PubChem CID:
445643
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