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折扣/货期| 货号：AG-40B-0095-C100 | 规格：100 ug | 目录价：￥3120 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Flagellin
别名:
FliC
产品描述:
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. It activates the innate immune system through the receptor Toll-like Receptor 5 (TLR5) and the intracellular protein NLRC4 (NLR family CARD domain-containing protein 4).
宿主来源:
Salmonella typhimurium strain 14028
靶标/特异性:
Binds to human and mouse TLR5 (Toll-like receptor 5).
产品浓度:
1mg/ml after reconstitution
保存温度:
+4°C
运输温度:
BI
产品形式:
solid
存储溶液:
Lyophilized. Contains PBS.
有效期:
Stable for at least 6 months after receipt when stored at -20°C.
产地:
瑞士
纯度:
>90% (SDS-PAGE)
生物活性:
Activation of TLR5 in human epithelial cell assays based on NF-kappaB luciferase fusions, on expression of IL-8 (CXCL8), CCL20, inducible nitric oxide synthase, beta-defensin 2 and matrilysin (MMP-7). Maturation of dendritic cells in in vitro and in vivoassays. Adjuvant activity on foreign antigens delivered by subcutaneous and intranasal routes in mice.
TLR5 can be stimulated in vitro by Flagellin at a concentration of 5-50ng /ml and in vivo at a starting concentration of 0.1-1µg /mouse.
内毒素水平:
<0.01EU/µg purified protein (LAL test; Lonza).
促销活动
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