Flagellin (NLRC4 Mutant) (rec.) MultiPack-其他重组蛋白-深圳欣博盛生物科技有限公司

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Flagellin (NLRC4 Mutant) (rec.) MultiPack

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-40B-0126-3010	规格：3 x 10 ug	目录价：￥4800
货号：AG-40B-0126-C010	规格：10 ug	目录价：￥2160

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Flagellin (NLRC4 Mutant) (rec.) MultiPack

别名:

FliC (NLRC4 Mutant)

产品描述:

Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. It activates the innate immune system through the receptor Toll-like Receptor 5 (TLR5) or the intracellular NLRC4 protein. The Flagellin (NLRC4 Mutant)(rec.) is only detected by TLR5 not by NLRC4.

宿主来源:

E. coli

靶标/特异性:

Detected by human and mouse TLR5 (Toll-like receptor 5). Not detected by mouse NLRC4 (Nod-like receptor [NLR] family caspase activation and recruitment domain [CARD] domain-containing protein 4).

产品浓度:

0.1mg/ml after reconstitution

保存温度:

+4°C

运输温度:

产品形式:

solid

存储溶液:

Lyophilized. Contains PBS.

有效期:

Stable for at least 6 months after receipt when stored at -20°C.

产地:

瑞士

纯度:

>95% (SDS-PAGE)

生物活性:

Activation of TLR5 in human epithelial cell assays based on NF-kappaB luciferase fusions, in vivo on expression of CCL20 or IL-6. TLR5 can be stimulated in vitro by Flagellin (NLRC4 mutant) (rec.) at a concentration range of 5-50ng/ml and in vivo at a starting concentration of 0.1-1µg/mouse. Does not activate NLRC4 as tested in bone-marrow mouse macrophages (in the presence of streptolysin O (SLO)). It can be used as negative control for NLRC4 signaling.

内毒素水平:

<0.01EU/µg purified protein (LAL test).

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