官网链接
折扣/货期| 货号：CDX-F0337-M005 | 规格：5 mg | 目录价：￥742 |
| 货号：CDX-F0337-M025 | 规格：25 mg | 目录价：￥2212 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
Flibanserin
别名:
1,3-Dihydro-1-[2-[4-[3-(trifluoromethyl)phenyl]-1-piperazinyl]ethyl]-2H-benzimidazol-2-one; BIMT 17; BIMT 17BS
产品描述:
Flibanserin is a full agonist of the serotonin 5-HT1A receptor and an antagonist of 5-HT2A (Ki=1nm and 49nM, respectively). It also binds to dopamine D4 receptors with Ki values ranging from 4-24nM, but demonstrates no affinity for the other 5-HT subtypes or other neurotransmitter receptors. Multifunctional serotonergic ligands like flibanserin that can enhance downstream release of dopamine and norepinephrine while concomitantly reducing serotonin release in the brain circuits that mediate symptoms of reduced sexual interest and desire, are being studied clinically for therapeutic potential to improve sexual functioning. Flibanserin was investigated as a novel, non-hormonal treatment for pre-menopausal women with Hypoactive Sexual Desire Disorder (HSDD). Flibanserin was also found to reduce L-DOPA-induced dyskinesia in a model of Parkinson‘s Disease.
宿主来源:
Synthetic
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
390.4
产品形式:
solid
产地:
瑞士
纯度:
>98% (HPLC)
CAS号:
167933-07-5
分子式:
C20H21F3N4O
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