货号:CHI-HF-211FLT3L-C050 | 规格:50 ug | 目录价:¥5180 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
FLT3 Ligand (human):Fc (mouse) (rec.)
别名:
FLT3L; FMS-like Tyrosine Kinase 3 Ligand
产品描述:
FMS-like tyrosine kinase 3 ligand (FLT3L) acts as a growth factor that increases the number of immune cells (lymphocytes (B cells and T cells)) by activating the hematopoietic progenitors. It binds to FLT3 (CD135) which is found on multipotent progenitor (MPP) and common lymphoid progenitor (CLP) cells in mice. FLT3L induces the mobilization of the hematopoietic progenitors and stem cells in vivo which may help the system to kill cancer cells. FLT3L is crucial for steady-state pDC (plasmacytoid dendritic cells) and cDC (classical dendritic cells) development. Deficiency of FLT3L causes a dramatic decrease in DC numbers, whereas increasing its availability increase in DC numbers.
宿主来源:
HEK 293 cells
保存温度:
+4°C
运输温度:
BI
产品形式:
solid
存储溶液:
Lyophilized from 0.2µm-filtered solution in PBS.
有效期:
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>98% (SDS-PAGE)
内毒素水平:
<0.06EU/µg purified protein (LAL test; Lonza).
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