Frizzled 6 antibody-多抗-深圳欣博盛生物科技有限公司

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Frizzled 6 antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX71521

规格：25μg

目录价：￥3800

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

Frizzled 6 antibody

别名:

frizzled class receptor 6 , FZ6 , FZD6 , HFZ6 , NDNC10 , Frizzled 6

反应种属:

Human

宿主来源:

Rabbit

实验应用:

IHC-P

同种型:

IgG

免疫原:

Synthetic 17 amino acid peptide from N-terminal extracellular domain of human Frizzled-6.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by affinity chromatography

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 0.1% Sodium azide.

生产商:

GeneTex

功能与背景:

This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.[provided by RefSeq, Aug 2011]

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