GALR2 antibody-多抗-深圳欣博盛生物科技有限公司

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GALR2 antibody

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX70681

规格：25μg

目录价：￥4000

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

GALR2 antibody

别名:

galanin receptor 2 , GAL2R , GALNR2 , GALR2 , Galanin Receptor 2

反应种属:

Human

宿主来源:

Rabbit

实验应用:

IHC-P

同种型:

IgG

免疫原:

Synthetic 18 amino acid peptide from 7th transmembrane domain of human GALR2.

克隆性:

Polyclonal

克隆号:

纯化方式:

Purified by affinity chromatography

偶联:

Unconjugated

产品浓度:

1 mg/ml (Please refer to the vial label for the specific concentration.)

保存温度:

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.

运输温度:

4°C

产品形式:

Liquid

存储溶液:

PBS, 0.1% Sodium azide.

生产商:

GeneTex

功能与背景:

Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways. [provided by RefSeq, Jul 2008]

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