| 货号:V5711-100UG | 规格:100 ug | 目录价:¥6652.1 |
| 货号:V5711-20UG | 规格:20 ug | 目录价:¥3082.1 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
GC Antibody / Group specific component / VDBP
产品描述:
Vitamin D-binding protein (DBP) is a multi-functional serum protein that binds to the plasma membranes of numerous cell types and mediates a variety of cellular functions. The locus of the DBP protein (also known as group-specific component protein or GC) is located at human chromosome 4q13.3. DBP functions in organ-specific transportation of vitamin D and its metabolites to the various target organs of the vitamin D endocrine system. In addition, DBP has immunomodulatory properties and is able to bind to the surface of leukocytes. DBP binds to the plasma membrane through a chondroitin sulfate proteoglycan. DBP serves as a co-chemotactic factor for C5a to enhance the chemotactic activity of C5a. DBP can also bind to globular Actin with high affinity and is involved in the clearance of Actin from the blood. DBP plays an important role in osteoclast differentiation. The diverse cellular functions of DBP require its cell surface binding ability to mediate different biological processes.
反应种属:
Human
宿主来源:
Mouse
实验应用:
IHC-P
同种型:
Mouse IgG, kappa
免疫原:
A portion of amino acids 1-200 from human Vitamin D binding protein was used as the immunogen for the GC antibody.
克隆性:
Monoclonal (mouse origin)
克隆号:
VDBP/9980
纯化方式:
Protein A/G affinity
保存温度:
Aliquot the GC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
产品形式:
Purified
存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
产地:
美国
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