GCK Antibody-多抗-深圳欣博盛生物科技有限公司

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GCK Antibody

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：63-280

规格：400 ul

目录价：￥8687.25

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

GCK Antibody

别名:

Glucokinase, Hexokinase type IV, HK IV, Hexokinase-4, HK4, Hexokinase-D, GCK

反应种属:

Human

宿主来源:

Rabbit

实验应用:

WB,IHC-P

同种型:

Rabbit Ig

克隆性:

Polyclonal

纯化方式:

This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

偶联:

Unconjugated

产品浓度:

batch dependent

保存温度:

Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

运输温度:

Blue Ice

产品形式:

Liquid

存储溶液:

Supplied in PBS with 0.09% (W/V) sodium azide.

产地:

美国

生产商:

Prosci

功能与背景:

Hexokinases phosphorylate glucose to produce glucose-6-phosphate, thus committing glucose to the glycolytic pathway. Alternative splicing of the gene for GCK results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in the gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), also called maturity onset diabetes of the young, type 2 (MODY2); mutations have also been associated with persistent hyperinsulinemic hypoglycemia of infancy (PHHI).

Accession #:

P35557

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