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折扣/货期| 货号：AG-CR1-3706-M001 | 规格：1 mg | 目录价：￥360 |
产品详情
* 以下信息仅供参考，详情请以原厂网站为准
产品名称:
GeA-69
别名:
N-(2-(9H-Carbazol-1-yl)phenyl)acetamide
产品描述:
Potent, selective, allosteric inhibitor of macrodomain 2 of poly-adenosine-diphosphate-ribose polymerase 14 (PARP-14 M2) (Kd=0.86µM, ITC (isothermal titration calorimetry) assay). PARP-14 is an anti-apoptotic pro-survival protein associated with inflammatory diseases and several types of cancer. Engages PARP-14 MD2 in intact cells displaces adenosine diphosphate ribose (ADPR) from PARP-14 M2 and prevents recruitment of the PARP-14 M2 to DNA damage sites.
保存温度:
+4°C
运输温度:
Ambient
预期分子量:
300.4
产品形式:
solid
产地:
瑞士
纯度:
>95%
CAS号:
2143475-98-1
分子式:
C20H16N2O
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