| 货号:40825-1 mg | 规格:1 mg | 目录价:¥375 |
| 货号:40825-10 mg | 规格:10 mg | 目录价:¥1849 |
| 货号:40825-25 mg | 规格:25 mg | 目录价:¥3685 |
| 货号:40825-5 mg | 规格:5 mg | 目录价:¥1206 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
Gefapixant
别名:
AF-219|MK-7264|Ro 4926219
产品描述:
A P2X3 receptor antagonist; inhibits agonist-induced P2X3 and P2X2/3 currents in 1321N1 cells co-expressing human P2X2 and P2X3 (IC50s = 153 and 220 nM, respectively) but does not inhibit P2X2 currents in the same cells at 10 µM; increases the paw withdrawal threshold and decreases weight-bearing discomfort in a rat model of CFA-induced inflammatory hyperalgesia and a rat model of neuropathic pain induced by sciatic nerve injury at 30 mg/kg; improves cardiac function, reduces cardiac TNF-α levels, and prevents cardiac fibrosis in a rat model of LAD branch ligation-induced myocardial infarction induced at 10 mg/kg
保存温度:
-20
运输温度:
-20
预期分子量:
353.39796
产品形式:
A solid
纯度:
≥98%
CAS号:
1015787-98-0
分子式:
C14H19N5O4S
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