GFR alpha-like Recombinant Protein-细胞因子、趋化因子与生长因子-深圳欣博盛生物科技有限公司

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GFR alpha-like Recombinant Protein

品牌：ProSci LLC

官网链接

说明书

折扣/货期

货号：11-410

规格：0.1 mg

目录价：￥10126.35

产品详情

* 以下信息仅供参考，详情请以原厂网站为准

产品名称:

GFR alpha-like Recombinant Protein

别名:

GFR alpha like,GFR alpha-like,GFRAL,GRAL

实验应用:

表达系统:

HEK293 cells

保存温度:

Lyophilized Protein should be stored at -20˚C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚C or -70˚C. Avoid repeated freeze-thaw cycles.

运输温度:

Blue Ice

产品形式:

Lyophilized

存储溶液:

PBS, pH7.4

产地:

美国

生产商:

Prosci

功能与背景:

GFR alpha-like is also known as GDNF family receptor alpha-like, GFRAL, C6orf144, UNQ9356, PRO34128. Growth differentiation factor-15 (GDF15) is a circulating protein that has been implicated in multiple biological processes, including energy homeostasis, body weight regulation, and cachexia driven by cancer and chronic disease. GDNF family receptor α-like (GFRAL) was recently identified as the neuronal brainstem receptor responsible for mediating the anorectic actions of GDF15. Brainstem-restricted receptor for GDF15 which regulates food intake, energy expenditure and body weight in response to metabolic and toxin-induced stresses . Upon interaction with its ligand, GDF15, interacts with RET and induces cellular signaling through activation of MAPK- and AKT- signaling pathways.

纯度:

>95% as determined by SDS-PAGE.

Accession #:

NP_997293.2

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