货号:CHI-MF-110GFRAL-C100 | 规格:100 ug | 目录价:¥6160 |
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
产品名称:
GFRAL (mouse):Fc (mouse) (rec.)
别名:
GDNF Family Receptor alpha-like; Gral; Glial Cellline-derived Neurotrophic Factor Receptor alpha-like; GFR alpha-like
产品描述:
GFRAL (GDNF receptor alpha-like) is a distant member of the GDNFR family of proteins. Mouse GFR alpha-like contains a 330aa extracellular domain. It is expressed on hindbrain neurons of the CNS and functions as an anti-apoptotic molecule during neuronal stress. GFRAL is a functional receptor for GDF15, facilitating weight-loss functions of the protein through c-Ret downstream signaling. GFRAL and GDF15 signaling is implicated in diet-based obesity and insulin resistance.
宿主来源:
HEK 293 cells
保存温度:
+4°C
运输温度:
BI
产品形式:
solid
存储溶液:
Lyophilized from 0.2µm-filtered solution in PBS.
有效期:
Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
产地:
瑞士
纯度:
>98% (SDS-PAGE)
生物活性:
Measured by its binding ability in a functional ELISA.
内毒素水平:
<0.06EU/µg purified protein (LAL test; Lonza).
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